干细胞疗法 修复生命的引擎
2016-09-04

   

Stem Cell Therapy: Supercharge the Heart

Cheryl Renee

SALT LAKE CITY, UT (Ivanhoe Newswire/WTVM)Heart researchers are excited about a new study that shows that patients’ own stem cells can be supercharged to fix damage. In the University of Utah study, there was a 37% reduction in the number of times heart failure patients went to the hospital or died. Researchers say that has never happened before.

 Utah Senator Ralph Okerlund did his work in the Capitol despite two heart attacks and congestive heart failure. But he didn’t feel well. 

Okerlund reveals, “If I walked from my house out to the mailbox across the street, I’d have to stop a couple of times on the way.”

Amit Patel, MD, MS, the Director of Clinical Regenerative Medicine at the University of Utah put the senator in the IX Cell DCM Cell Therapy.

“We basically took the certain cells that were still alive and put them in a healthy environment and basically had their own body start healing the heart,” describes Dr. Patel. 

Dr. Patel took three tablespoons of bone marrow from patients, and put them in a bioreactor for twelve days to supercharge them.

“So all the young stem cells grew up and all the old weaker cells that had the effects of aging, diabetes and all that died off,” explains Dr. Patel. 

Then he injected 100 to 200 million healthy stem cells into patients’ hearts after mapping out damaged areas. The supercharged cells triggered an immune function to help the heart heal itself. Half the 114 patients in the study got the therapy. Senator Okerlund knew he was one after a few months. 

“I still am not out running races. I won’t be running any marathons with the damage that has been done to my heart, but I feel well enough now that I can kind of do what I want as long as I move slowly,” says Okerlund. 

He’s excited to have been part of the study and hopes it helps many other people.

The patients who got the placebo in Dr. Patel’s current study can now get the treatment because it worked. Dr. Patel said a much larger study needs to be done to prove the cell therapy works before it’s available to the general public.


干细胞疗法 修复生命的引擎


【看中国纽约工商讯】据犹他州盐湖城艾芬豪新闻专线报导,心脏研究人员对一项新研究表示非常兴奋。该研究表示,患者自身的干细胞可以通过增压以修复损伤。在犹他大学的一项研究中,因患心力衰竭住院或死亡的人数降低了37%。研究人员说,在这之前从未发生过。

犹他州参议员Ralph Okerlund尽管两次心脏病发作,还有充血性心力衰竭,但他仍然在国会工作,只是感觉不太好。

Okerlund透露:「如果我从家走到街对面的邮箱,我必须在路上停歇几次。」

Amit Patel,医学博士,医学硕士,犹他大学临床再生医学主任,对参议员进行了第九细胞DCM细胞疗法。

Patel博士说:「我们基本上采取了仍然活着的某些细胞,并把他们放在一个健康的环境里,基本上用它们自己的主体开始愈合心脏。」

Patel博士从患者体内取了三汤匙量的骨髓,并将它们放在一个生物反应器里十二天,然后对他们进行增压。「结果所有年轻的干细胞成长了,所有旧的、对老化和糖尿病有影响的细胞都死掉了」 Patel博士解释说。

在映射出受损区域后,他将100至2亿个健康的干细胞注射到了患者的心脏。机械增压的细胞引发了免疫功能,帮助心脏进行自我修复。在研究的114例患者中,有一半的患者得到了治疗。Okerlund议员知道他是几个月后的其中一位。

Okerlund说:「我还没有跑比赛。我不会带着伤害我心脏的危险做任何马拉松,但我现在已经感觉很好了,只要我慢慢移动,我可以做任何我想做的事。」

Okerlund议员很高兴能成为这项研究的一部分,并希望该研究可以帮助更多其他的人。

在Patel博士目前的研究中得到安慰的患者们,现在可以得到完全治疗,因为这项研究成功了。但Patel博士还说,在提供给公众之前,还需要做更大的研究,用以证明干细胞疗法是可行的。

事实上,许多研究人员和病人及其亲属都确信,干细胞是解决再生问题的一条出路。毕竟,当一块心肌因心脏病发作而缺氧时就会坏死,没有甚么药物可以使它复生。

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    来源: 看中国 责编: Kitt

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